On the sidelines of the United Nations General Assembly (UNGA) in New York, the U.S. Chamber of Commerce, in collaboration with the American Chamber of Commerce in Ghana (AmCham Ghana), convened a high-level U.S.–Ghana Executive Business Dialogue. The 25th September event was graced by H.E. President John Dramani Mahama, who reaffirmed his government’s commitment to creating a more attractive and enabling environment for foreign investment in Ghana.

Renewed Commitment to Investment Reforms

In his remarks, President Mahama underscored reforms designed to open Ghana further to global investors. The comprehensive dialogue covered opportunities in energy, healthcare, mining, technology, and agriculture in Ghana, one of West Africa’s fastest-growing markets. The discussions underscored Ghana’s determination to strengthen U.S. commercial partnerships, with President Mahama reaffirming his campaign message that the country is “open for business.”

He emphasized the removal of minimum capital requirements for foreign entry (except for sectors reserved for Ghanaians), the ongoing digital transformation of the Ghana Investment Promotion Centre (GIPC) to enable 24-hour business registration, and the planned introduction of electronic visas from 2026. These measures, he stressed, will ease the process of doing business and position Ghana as the “gateway to Africa” for U.S. investors.

Business Leaders Engage on Opportunities

The roundtable brought together leading American multinationals and Ghanaian corporate leaders across energy, aviation, technology, healthcare, and financial services. Discussions centered on deepening partnerships, expanding trade and investment flows, and addressing shared challenges in the business environment. Companies welcomed the government’s reforms and expressed optimism about the opportunities to scale their investments in Ghana.

For U.S. firms, the discussions signal a stronger and more predictable investment climate in Ghana, backed by the President’s commitment to reforms. The removal of capital entry requirements for most sectors lowers barriers for new entrants, while the push toward 24-hour business registration and future e-visas reduces friction for cross-border operations.

Trade policy is also central. The possible renewal of the African Growth and Opportunity Act (AGOA) will ensure continued duty-free access to the U.S. market, which is vital for Ghanaian exports and, by extension, for U.S. firms building supply chains and joint ventures in the country. Meanwhile, Ghana’s role as host of the AfCFTA Secretariat gives U.S. companies a strategic hub into Africa’s 1.4-billion-person market.

Sector by sector, opportunities are opening. In energy and mining, U.S. technology and service providers can partner with Ghana to modernize infrastructure and drive sustainable practices. In healthcare, demand for pharmaceuticals, digital health solutions, and advanced

medical equipment remains high. Agriculture and agribusiness present avenues for U.S. firms to apply innovation across supply chains. And in technology, Ghana’s youthful population and digital transformation create fertile ground for American innovation and investment.

Ultimately, the roundtable reinforced that Ghana is positioning itself as the entry point for U.S. companies into Africa. For American businesses, this is both a market opportunity and a strategic imperative: those who move early will be best placed to shape and benefit from the continent’s next wave of grow

AmCham Ghana’s Role

As the convener on the Ghana side, AmCham Ghana facilitated candid exchanges between policymakers and the private sector. The Chamber reaffirmed its role as a trusted partner that connects U.S. businesses to Ghana’s opportunities, while ensuring that members’ concerns are constructively addressed through advocacy and dialogue. The event further highlighted the Chamber’s growing influence as a neutral platform that strengthens U.S.–Ghana economic relations.

AmCham Ghana is uniquely positioned to serve as the bridge between U.S. businesses and Ghana’s evolving investment landscape. At the New York roundtable, the Chamber played a convening role—bringing the President, senior policymakers, and corporate leaders into one room for frank and solution-oriented dialogue.

Going forward, AmCham’s role will be threefold:

1. Advocacy – ensuring that the concerns of U.S. investors are voiced at the highest levels of government, particularly on regulatory clarity, taxation, and trade policy.

2. Facilitation – creating platforms where members can explore partnerships, expand into new sectors, and connect with Ghana’s AfCFTA advantage as a regional gateway. It will also facilitate a U.S. Ghana Commercial dialogue with key Ministries and Agencies to provide members with a formalized high level platform to influence policy and gain insights to the Ghana’s evolving economy

3. Support – equipping member companies with practical tools, market intelligence, and policy insights to reduce business risks and unlock opportunities.

In essence, AmCham Ghana will remain a trusted partner for U.S. companies, enabling them not just to enter the market but to thrive, while also strengthening Ghana’s position as a reliable investment destination in Africa

Looking Ahead

The success of the New York roundtable not only reaffirmed Ghana’s openness for business but also set the tone for sustained U.S.–Ghana cooperation. With a renewed focus on investment facilitation, digital reforms, and inclusive growth, the Chamber and its partners will continue to play a pivotal role in unlocking opportunities that benefit both economies.

As the President succinctly put it, “Ghana is indeed open for business.